Oleandomycin

Zoetis Mastalone (containing oleandomycin) is indicated for the local treatment of acute and chronic mastitis in lactating dairy cattle.

Treatment of Mastitis: Mastalone is a broad-spectrum antibiotic combination used to treat acute and chronic bacterial mastitis.
Target Microorganisms: Effective against a wide range of bacteria commonly associated with bovine mastitis, including Staphylococci and Streptococci species.
Second-Line Treatment: Due to it containing critically important antibiotics, it is often reserved for severe cases or as a second-line treatment when other, less critical, antibiotics have failed or are clinically determined to be ineffective.
Reducing Inflammation: The formulation includes prednisolone, an anti-inflammatory agent, which helps to reduce udder inflammation and hasten the recovery of milk quality.

Administered directly into the udder via the teat canal. The full course of treatment involves 3 infusions per infected quarter.

Milk the udder completely: Ensure the affected quarter(s) are thoroughly stripped out before treatment.
Clean and disinfect the teat: Wash and dry the udder and teats thoroughly. Use the alcohol swabs provided to clean and disinfect the teat orifice to prevent introducing new bacteria.
Infuse the suspension:
- Remove the cap from the syringe nozzle.
- Carefully insert the nozzle tip into the teat opening (some products offer a choice of partial or full insertion).
- Squeeze the entire contents of the syringe slowly into the quarter using gentle and continuous pressure.
Massage the udder: Gently massage the treated quarter from the bottom upwards, to help disperse the medication into the milk cistern.
Repeat treatment: The treatment should be repeated at 24-hour intervals (or every 12 hours depending on the specific product’s instructions and the severity of the case) for a total of three treatments.

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