Boehringer Marquis (ponazuril) is indicated for CNS and gastrointestinal infections caused by protozoal parasites in horses.
INDICATIONS
Equine Protozoal Myeloencephalitis (EPM): A neurological disease in horses caused by Sarcocystis neurona.
Off-Label:
Coccidiosis: Intestinal infections by Cystoisospora and Eimeria in dogs, cats, rabbits, and piglets, often causing diarrhea.
ADMINISTRATION
Marquis is formulated as a 15% w/w oral paste designed for easy and accurate dosing in horses.
- Dosing: The paste is typically administered at a dose rate of 5 mg/kg of body weight once daily for at least 28 consecutive days, or until clinical signs resolve.
- Method:
- The horse’s weight is determined, and the dosage ring on the syringe plunger is set to the correct weight marking.
- The tip of the syringe is introduced into the side of the horse’s mouth, in the space between the front and back teeth.
- The entire dose of paste is deposited onto the back and top of the horse’s tongue.
- The horse’s head is gently raised for a few seconds to encourage swallowing.
- Loading Dose: An initial loading dose of 15 mg/kg may be recommended for the first dose only to help the medication reach effective levels in the bloodstream and cerebrospinal fluid faster.
