Tildipirosin injection is indicated for the treatment and control of respiratory diseases in cattle and swine.
INDICATIONS
Cattle (Bovine Respiratory Disease – BRD)
Tildipirosin is indicated for the treatment of BRD and the control (prevention) of respiratory disease in cattle at high risk of developing BRD. It is effective against bacterial pathogens such as Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni.
Swine (Swine Respiratory Disease – SRD)
In swine, tildipirosin is indicated for the treatment and metaphylaxis (control/prevention in a group) of SRD associated with bacteria like Actinobacillus pleuropneumoniae, Pasteurella multocida, Bordetella bronchiseptica, and Haemophilus parasuis.
ADMINISTRATION
- Route: Subcutaneous injection only.
- Site: The injection should be given in the neck region.
- Dosage: The standard dosage is 4 mg of tildipirosin per kg of body weight (equivalent to 1 mL per 100 lbs of body weight in the US or 1 mL per 45 kg in other regions).
- Volume: Do not inject more than 10 mL into a single injection site. For animals over 450 kg (approx. 1000 lbs), the dose should be divided across multiple injection sites.
- Technique: A common method for subcutaneous injection is to use the “tenting” technique, where you pinch a fold of skin and insert the needle into the created pocket.
- Contraindications:
- It is specifically contraindicated and fatal adverse events have been reported in swine when the cattle formulation (180 mg/mL) is used, and vice versa for the swine formulation.
- Do not use in female dairy cattle 20 months of age or older or in calves intended for veal.
- Do not use concurrently with other macrolides or lincosamides, as cross-resistance may occur.
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