Tolfenamic Acid VMD (tolfenamic acid) is a non-steroidal anti-inflammatory drug (NSAID) used to manage pain and inflammation in dogs, cats, cattle and pigs. Works by inhibiting cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2, the enzymes responsible for producing inflammatory mediators like prostaglandins and thromboxanes, leading to a reduction in inflammation, pain, and fever.