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Triclabendazole

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Triclabendazole

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Triclabendazole Bolus

Triclabendazole is used to treat and control parasitic iinfections in cattle and sheep. including all stages of liver flukes (Fasciola hepatica and Fasciola gigantica), and acute, subacute, and chronic fascioliasis. Administered orally, often as a single dose. An FAO/WHO Veterinary Medicine.

Triclabendazole bolus is an anthelmintic medication primarily used in cattle, sheep, and goats for the treatment and control of fascioliasis, an infection caused by liver flukes (Fasciola hepatica and F. gigantica). Administered orally, often as a single dose.

  • Target Parasites: Triclabendazole is highly effective against all stages of the liver fluke, including early immature, immature, and adult forms. This makes it a crucial tool for both the treatment of acute and chronic infections.
  • Mechanism: As a benzimidazole derivative, it works by binding to the parasite’s beta-tubulin protein, which inhibits microtubule formation and damages the parasite’s cellular transport functions, ultimately killing it.
  • Spectrum: It is a narrow-spectrum dewormer, primarily effective only against flukes, and generally not against roundworms, tapeworms, or external parasites when used alone. It is often combined with other anthelmintics (like Levamisole) to create a broader spectrum treatment for various gastrointestinal and lungworms.
  • Benefits: When used effectively, it helps reduce clinical signs of infection, improves weight gain, and can help maintain normal milk production and fertility in livestock.
  • Safety: It is considered safe for use during pregnancy and lactation at recommended dosages, though withdrawal periods for meat and milk must be observed to avoid residues in the food chain. 

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