AXIENCE brand Trilorale (trilostane) is a veterinary medicine used for the treatment Cushings Disease in dogs, a condition where the adrenal glands produce too much cortisol. Trilorale blocks the production of cortisol, thereby reducing the excessive cortisol levels in the dog's body. This helps manage the symptoms associated with Cushing's disease, especially increased thirst and urination. An EU Authorised medicine.