• Cattle & Calves: Calf diphtheria, foot rot, shipping fever, and actinobacillosis.
• Pigs: Atrophic rhinitis (often in combination with other drugs), necrotic enteritis, and cervical abscesses.
• Sheep & Goats: Pasteurellosis and respiratory infections.
• Poultry: Infectious coryza, fowl cholera, and pullorum disease.
• Horses & Dogs: Strangles (horses) and various streptococcal infections. 

ADMINISTRATION

1. Route: Typically given via subcutaneous (SC), intramuscular (IM), or slow intravenous (IV) injection.
2. Hydration: Ensure animals have constant access to adequate drinking water to prevent crystalluria (kidney stone formation).
3. Withdrawal Periods: Standard 2026 safety protocols typically require 8–18 days for meat and 3–7 days for milk, though this varies by product concentration and regional regulations.
4. Contraindications: Not for use in animals with severe liver or kidney damage, or those with known hypersensitivity to sulfonamides.