Ticarcillin (component)

TRONATE-CV Injection (ticarcillin and clavulanic acid) is indicated for the treatment of bacterial infections in horses and dogs.

Intrauterine Infections (Mares): Used for treatment of endometritis in horses, especially infections caused by β-hemolytic streptococci.
Severe Systemic Infections: The combination is used to treat serious infections in various animals, including pneumonia, bone infections (osteomyelitis), and soft tissue infections.
Topical Ear Infections (Dogs): A compounded ticarcillin-clavulanic acid solution (often under the brand name Timentin) is used topically to treat Pseudomonas otitis (ear infections), which are frequently resistant to other antibiotics.
Mixed Infections: Because of its broad spectrum of activity against both Gram-positive and Gram-negative bacteria, it is particularly useful for mixed infections or for initial therapy before the specific causative organism is identified.

Restraint & Prep: Secure the animal and clip hair at the injection site (often the neck or ribs).
Tenting the Skin: Gently lift a fold of skin to create a “tent”.
Needle Insertion: Insert a short needle (0.5-1 inch) at a 45-degree angle into the base of the tent, parallel to the skin.
Aspirate: Pull back slightly on the plunger; if blood appears, the needle is in a blood vessel, and you must reposition.
Inject: Slowly push the plunger to inject the medication.

Intramuscular (IM)

Site Selection: Deep into a large muscle, using a long enough needle to reach it.
Aspirate: Check for blood as with SQ injections.
Inject: Slowly depress the plunger, then remove the needle.

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