Josamycin tablets are indicated in poultry and swine for the prevention and treatment of a variety of bacterial infections.
INDICATIONS
- Poultry (Chickens and Turkeys):
- Chronic Respiratory Disease (CRD): Effective against respiratory infections caused by Mycoplasma gallisepticum.
- Infectious Sinusitis: Treatment of inflammation in the sinuses.
- Infectious Synovitis: Treatment of joint-related infections.
- Arthritis: Used to treat joint inflammation caused by susceptible Gram-positive germs.
- Swine (Pigs):
- Mycoplasmal Pneumonia: Prevention and treatment of chronic respiratory diseases.
- Arthritis: Treatment of joint infections caused by Mycoplasma species.
ADMINISTRATION
- Direct Oral Dosing: Tablets are given by mouth. For larger animals, a balling gun can be used to ensure the tablet is swallowed.
- Whole Tablet Requirement: To prevent degradation by stomach acid, tablets should generally be administered whole. Crushing or dividing tablets can reduce their efficacy, as macrolides are sensitive to gastric acids.
- Empty Stomach vs. Food: For maximum absorption in some species, it is recommended to administer the dose on an empty stomach (at least 1 hour before or 2–3 hours after a meal).
- Divided Dosing: The daily dose is often split into two divided doses (e.g., morning and evening).
- Hydration: Always follow oral administration with a small amount of water to ensure the tablet reaches the stomach and to reduce the risk of esophageal irritation.
