Bovine Respiratory Syncytial Virus Vaccine

HIPRA NASYM is a live attenuated vaccine for cattle designed to actively immunize against Bovine Respiratory Syncytial Virus (BRSV).

Primary Indication: Reduction of respiratory clinical signs and virus shedding caused by BRSV.
Onset of Immunity: 21 days after a single nasal dose.
Administration Routes:
- Nasal (Intranasal): 1 ml in each nostril (2 ml total) for calves from 9 days of age.
- Intramuscular: 2 ml injection for calves from 10 weeks of age (two-dose schedule required).
Duration of Immunity: 2 months post-vaccination, with recommendations for revaccination.
Safety: The vaccine is effective in the presence of maternally derived antibodies (MDA).

Intranasal (IN) Route (Primary Protection): For calves from 9 days of age. Spray of the reconstituted vaccine into each nostril using an applicator.
Intramuscular (IM) Route (Alternative/Boosters): For cattle from 10 weeks of age. Administer a single injection into the muscle.
Combined Protocol: Intranasal vaccination at 9 days, followed by an intramuscular booster 2 months later provides up to 8 months of immunity.
Reconstitution: The freeze-dried vaccine must be mixed with the provided solvent. Shake well to ensure a homogeneous, slightly yellowish suspension before use.
Precautions: Use sterile needles/syringes and a new applicator for each animal to avoid contamination.