Enilconazole is indicated for the treatment of fungal infections in domestic animals, most notably dermatophytosis (ringworm) and nasal aspergillosis.
INDICATIONS
Enilconazole topical solution Imaveral is indicated for the treatment of dermatophytosis (ringworm) in cattle, horses, and dogs. Enilconazole is a synthetic broad-spectrum antifungal agent effective against common dermatophytes such as:
- Trichophyton verrucosum
- Trichophyton mentagrophytes
- Trichophyton equinum
- Microsporum canis
- Microsporum gypseum
In addition, it has an off-label (extra-label) use for:
- Nasal aspergillosis (a severe fungal infection of the nasal sinuses) in dogs and horses, where it is infused directly into the nasal cavity.
- Environmental decontamination of animal bedding, stalls, cages, and other materials to help prevent the spread and recurrence of fungal spores.
ADMINISTRATION
- Treatment of Fungal Skin Infections (Dermatophytosis/Ringworm): Enilconazole is commonly used as a wash or dip for dogs, cats, cattle, and horses.
- Preparation: The concentrated solution (typically 10%) is diluted in 50 parts of lukewarm water to yield a 0.2% emulsion.
- Application: The diluted solution is applied topically to the animal’s entire body, typically four times at 3- to 4-day intervals. Long-haired animals should be clipped first to ensure the solution reaches the skin.
- Technique: The solution should be rubbed thoroughly against the direction of hair growth to ensure the skin is thoroughly wet. Crusted areas should be brushed gently with a brush soaked in the solution to remove debris. The solution is generally not rinsed off.
- Treatment of Nasal Aspergillosis: In dogs and horses, enilconazole has been successfully instilled directly into the nasal sinuses or guttural pouches through indwelling catheters to treat fungal infections.
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