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Polymixin E (colistin)

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Polymixin E (colistin)

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COLISTIN-VET Soluble Powder

COLISTIN-VET Soluble Powder (Polymixin E) is administered orally via drinking water or liquid feed to treat and manage gastrointestinal infections caused by susceptible Gram-negative bacteria, particularly E. coli and Salmonella spp. It is intended for use in pigs, calves, sheep, goats, rabbits, and poultry. A WOAH Veterinary Medicine.

Polymyxin E (Colistin) soluble powder is indicated for gastrointestinal infections in pigs, calves, sheep, goats, rabbits, and poultry.

INDICATIONS

  • Preparation: The powder is mixed with a specific volume of clean, fresh water or milk replacer according to the manufacturer’s or veterinarian’s recommended dilution ratios. It is important to ensure the product is thoroughly dissolved.
  • Delivery: The medicated water/milk is provided as the sole source of drinking fluid for the animals during the treatment period.
  • Monitoring: Water or feed consumption should be monitored frequently to ensure that the animals receive the correct dosage based on their body weight.
  • Duration: The duration of treatment is typically 3 to 7 days, and should not exceed the minimum time necessary for treating the disease.
  • Freshness: Medicated water should be freshly prepared every 24 hours to maintain potency. 

ADMINISTRATION

  • Administration Method: The powder is dissolved in a specific amount of drinking water or milk replacer to create a medicated solution, which becomes the sole source of drinking water during the treatment period. It can also be mixed into feed.
  • Targeted Conditions: Due to its poor absorption from the intestinal tract, colistin sulfate acts locally within the gut lumen, making it effective for treating enteric diseases.
    • Pigs: Used for post-weaning diarrhea, white scours, and piglet paratyphoid.
    • Poultry: Used for colibacillosis, fowl cholera, fowl typhoid, and pullorum disease.
    • Calves, Sheep, Goats: Used for gastrointestinal infections and diarrhea in pre-ruminant animals.
  • Dosage: Dosage varies by species, weight, and infection severity.
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