Polymixin E (colistin)

Polymixin E (colistin) is indicated for gastrointestinal infections in pigs, calves, sheep, goats, rabbits, and poultry.

Preparation: The powder is mixed with a specific volume of clean, fresh water or milk replacer according to the manufacturer’s or veterinarian’s recommended dilution ratios. It is important to ensure the product is thoroughly dissolved.
Delivery: The medicated water/milk is provided as the sole source of drinking fluid for the animals during the treatment period.
Monitoring: Water or feed consumption should be monitored frequently to ensure that the animals receive the correct dosage based on their body weight.
Duration: The duration of treatment is typically 3 to 7 days, and should not exceed the minimum time necessary for treating the disease.
Freshness: Medicated water should be freshly prepared every 24 hours to maintain potency.

Administration Method: The powder is dissolved in a specific amount of drinking water or milk replacer to create a medicated solution, which becomes the sole source of drinking water during the treatment period. It can also be mixed into feed.
Targeted Conditions: Due to its poor absorption from the intestinal tract, colistin sulfate acts locally within the gut lumen, making it effective for treating enteric diseases.
- Pigs: Used for post-weaning diarrhea, white scours, and piglet paratyphoid.
- Poultry: Used for colibacillosis, fowl cholera, fowl typhoid, and pullorum disease.
- Calves, Sheep, Goats: Used for gastrointestinal infections and diarrhea in pre-ruminant animals.
Dosage: Dosage varies by species, weight, and infection severity.

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