Pseudorabies-Aujeszky’s Virus Vaccine

Pseudorabies (Aujeszky’s Disease) virus (PRV) vaccine is indicated for the prevention and control of PRV in domestic pig populations.

Disease Control in Swine Herds: Used as both a preventive measure in at-risk areas and a control measure during an acute outbreak.
Age-Specific Clinical Signs: PRV causes different symptoms depending on the pig’s age. Vaccination helps protect against:
- High Mortality and Neurological Signs in Piglets: Suckling piglets are highly vulnerable to fatal neurological disease.
- Respiratory Illness in Grower-Finisher Pigs: Older pigs typically develop respiratory signs and pneumonia.
- Reproductive Failure: In sows, the virus can cause embryonic death, abortions, stillbirths, and the birth of weak piglets.
Differentiation of Infected from Vaccinated Animals (DIVA Strategy): Modern “marker” vaccines are used in conjunction with specific diagnostic tests (gE ELISAs), which is crucial for monitoring and successful disease eradication programs.
Specific Animal Groups:
- Breeding herds (sows and boars) are often vaccinated quarterly.
- Piglets may receive intranasal immunization, especially during the first week of life.
- New stock (gilts and boars) should be bought from disease-free farms and vaccinated upon arrival or during quarantine

Intramuscular (IM) injection: This is a common method where the vaccine is injected into a muscle.
Intranasal (IN) administration: This route can induce local immunity at the site of viral entry.
Subcutaneous (SC) injection: The vaccine is injected into the loose skin, for example, behind the shoulder.
Intradermal (ID) administration: This method involves injecting a small dose into the dermis, often using a needleless device. This method requires less animal constraint and can be verified by a small papule at the injection site.

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