INDICATIONS

• Cattle & Calves:
  • Respiratory Infections: Bacterial pneumonia and Bovine Respiratory Disease Complex (Shipping Fever).
  • Enteric Issues: Colibacillosis (Bacterial Scours/diarrhea) caused by E. coli.
  • Soft Tissue: Necrotic pododermatitis (Foot Rot) and Calf Diphtheria.
  • Reproductive/Mammary: Acute Metritis and Acute Mastitis (Streptococcus spp.).
• Swine:
  • Bacterial Pneumonia: Often caused by Pasteurella spp..
  • Septicemia: Systemic bacterial infections.
  • Enteric Infections: Porcine Colibacillosis (Bacterial Scours).
• Sheep & Goats:
  • Enteric & Respiratory: Bacterial enteritis and acute respiratory infections.
  • Coccidiosis: Treatment and control of protozoal infections.
• Poultry (Chickens, Turkeys, Ducks):
  • Coccidiosis: Specifically Caecal Coccidiosis in chickens.
  • Respiratory: Infectious Coryza and secondary bacterial infections associated with CRD (Chronic Respiratory Disease).
  • Other: Acute Fowl Cholera, Pullorum disease, and Anatipestifer Disease in ducks.
• Horses:
  • As an aid in treating Strangles, Navel Ill, Joint Ill (septic arthritis), and bacterial enteritis. 

ADMINISTRATION

• Intravenous (IV) Injection: Typically used for severe or life-threatening infections in cattle and livestock to achieve therapeutic blood levels rapidly. It is usually administered “moderately slow” into the jugular vein.
• Subcutaneous (SQ) or Intramuscular (IM) Injection: Often used for convenience in treating calves, swine, sheep, and poultry.
• Oral (Off-label/Liquid Form): While formulated for injection, some liquid sodium sulfamethazine preparations are also used orally by adding them to drinking water or feed for poultry and livestock. 

1. Dosing Schedule: Usually involves a higher initial “loading dose” followed by daily maintenance doses (often half the initial amount) for 2 to 5 consecutive days.
2. Hydration: Treated animals should have free access to water to prevent the formation of sulfonamide crystals in the kidneys.
3. Preparation: Some concentrated solutions are highly alkaline and may require dilution or specific handling to avoid tissue irritation.