MSD Prestige Tetanus Toxoid vaccine is indicated for horses, cattle, swine, and sheep, to protect against the tetanus disease.

INDICATIONS

• Primary Vaccination: For initial immunization, a two-dose series is administered, with the second dose given 3-4 weeks after the first.
• Annual Revaccination: Annual booster shots are a common practice and generally recommended to maintain protection. The American Association of Equine Practitioners (AAEP) considers it a core vaccination for all horses yearly.
• At the Time of Injury or Surgery: A booster dose is indicated for any vaccinated animal that sustains a deep wound, puncture, or undergoes surgery, regardless of the time elapsed since the last annual booster. This helps to rapidly increase antibody production.
• Pregnant Mares: It is safe for use in pregnant mares and is often administered as a single dose during the third trimester of pregnancy (4 to 6 weeks before foaling). This transfers passive immunity to the foal through the colostrum.

ADMINISTRATION

Dosage and Schedule

• Horses, Cattle, and Swine: Administer a 1 mL dose.
• Sheep and Smaller Equine Breeds (e.g., Shetland ponies): Administer a 0.5 mL dose.
• Primary Vaccination Series:
  • First dose: Initial injection at the appropriate age (generally 6 months or older for healthy animals).
  • Second dose: Repeat with a single dose 3 to 4 weeks after the first.
• Revaccination: Historically, an annual booster has been recommended, though the specific need for annual revaccination for this product has not been strictly established; consult a veterinarian for the best frequency for your animal. 

1. Preparation: Shake the vial well before use to ensure the suspension is homogenous.
2. Storage: Store the vaccine at 2°–8°C (35°–46°F) and do not allow it to freeze.
3. Site Selection: Inject deep into the muscle (e.g., the neck for horses).
4. Asepsis: Always use a sterile needle and syringe for each animal to prevent cross-contamination.