Acepromazine

Acepromazine maleate injection is indicated as a tranquilizer/sedative and a pre-anesthetic agent in dogs, cats, and horses.

Tranquilization and Restraint: To help control intractable or fractious animals during various procedures, including clinical examinations, treatments, grooming, sample collection (e.g., blood draws), X-rays, and minor surgical procedures.
Pre-anesthetic Agent: Used before major or minor surgery to produce sedation, muscle relaxation, and to reduce the required doses of general anesthetics, which enhances and prolongs their effects.
Adjunct to Local Anesthesia: Used in conjunction with local anesthesia for procedures such as castration, ocular surgery, or applying casts in horses.

DOGS & CATS

Restraint: Aids in controlling fractious (unmanageable) animals during examinations, treatments, grooming, X-rays, and minor surgical procedures.
Pre-anesthetic: Used before general anesthesia to enhance and prolong the effects of anesthetics, thereby reducing the required dosage of general anesthesia.
Anti-emetic: Helps control vomiting associated with motion sickness.
Anti-itching: Alleviates itching as a result of skin irritation (though more effective anti-itch medicines are available).
Behavioral Issues: Can be prescribed to control nervousness, excessive vocalization, and excitable behavior, particularly prior to potentially stressful events like veterinary visits.

HORSES

Restraint and Transport: Aids in controlling nervous or fractious horses during examination, treatment, loading, and transportation.
Adjunct to Local Anesthesia: Particularly useful when used with local anesthesia for minor procedures like castration, neurectomy, or applying casts.
Laminitis: May be used off-label in the early treatment of laminitis due to its ability to dilate blood vessels and potentially improve circulation in the hoof.
Exertional Rhabdomyolysis: Sometimes used as a preventative or part of the treatment for “tying up” in horses (exertional rhabdomyolysis) due to its muscle relaxant and vasodilatory properties.

Injection (Intravenous, Intramuscular, Subcutaneous): Injections are generally administered by a veterinarian in a hospital setting.
- Intravenous (IV) injections should be administered slowly, allowing about 15 minutes for the full effect to be seen.
- Intramuscular (IM) and subcutaneous (SC) injections are also common routes, with intramuscular injections sometimes causing a brief stinging sensation.

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