Moxidectin is an antiparasitic medication used to treat and prevent internal and external parasites, primarily in cattle, sheep, and dogs.

INDICATIONS

for Cattle

• Gastrointestinal Roundworms: Effective against adults and L4 larvae of species such as Ostertagia ostertagi, Haemonchus placei, Trichostrongylus axei, and Cooperia species.
• Lungworms: Controls Dictyocaulus viviparus (adults and L4 larvae).
• Cattle Grubs: Targets parasitic larvae of Hypoderma bovis and Hypoderma lineatum.
• Mites: Specifically indicated for psoroptic mange (Psoroptes ovis).
• Lice: Effective against sucking lice such as Linognathus vituli and Solenopotes capillatus.
• Persistent Activity: Provides protection from reinfection for up to 42 days for certain species like lungworms. 

• Heartworm Prevention: Prevents heartworm disease caused by Dirofilaria immitis.
• Hookworm Treatment: Indicated for the treatment of existing larval and adult infections of Ancylostoma caninum and Uncinaria stenocephala present at the time of injection. 

ADMINISTRATION

• Route: It is given as a subcutaneous injection, meaning under the loose skin.
• Injection Site (Cattle): Typically given in the left or right side of the neck or the loose skin in front of or behind the shoulder.
• Injection Site (Dogs): Determined by the vet.
• Dosing: The dosage is calculated based on the animal’s body weight to ensure effectiveness and safety.

• In Dogs: The sustained-release injection is primarily used for:
  • Heartworm prevention: Provides protection for 6 or 12 months with a single dose.
  • Hookworm treatment and control.
  • Dogs must be tested for existing adult heartworm infection before receiving the injection, as using it in an infected dog can cause severe reactions.
• In Cattle and Sheep: It is used for the treatment and control of a wide range of parasites, including:
  • Gastrointestinal roundworms (e.g., Ostertagia ostertagi, Haemonchus placei).
  • Lungworms (Dictyocaulus viviparus).
  • Cattle grubs (Hypoderma bovis, Hypoderma lineatum).
  • Mites (Psoroptes ovis) and lice (Linognathus vituli, Solenopotes capillatus).
  • It offers prolonged, persistent activity, protecting against reinfection for several weeks to months, depending on the parasite.