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Sulfadiazine & Trimethoprim Bolus

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Sulfadiazine & Trimethoprim Bolus

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Sulfadiazine & Trimethoprim Bolus

Sulfadiazine & Trimethoprim bolus are an antibiotic/antimicrobial combination used to treat bacterial, and some protozoal infections in horses, cattle, sheep, and goats. The bolus work by inhibiting folic acid synthesis in bacteria, preventing their growth and reproduction.  

Sulfadiazine & Trimethoprim bolus are indicated for treating bacterial infections in cattle, sheep, goats, swine, horses, dogs, and cats.

INDICATIONS

  • Respiratory tract infections: Including pneumonia, bronchitis, rhinitis, and strangles in horses.
  • Gastrointestinal tract infections: Such as bacterial scours, neonatal diarrhea, salmonellosis, and gastroenteritis.
  • Urinary and reproductive tract infections: Including cystitis, vaginitis, urethritis, nephritis, metritis, and post-parturient infections.
  • Other infections:
    • Severe mastitis and bacterial agalactia in sows.
    • Skin and soft tissue infections, such as wound infections and abscesses.
    • Infectious pododermatitis (foul-in-the-foot or foot rot) in cattle.
    • Infections of the eye, ear, and mouth.
    • Certain protozoal infections like coccidiosis and toxoplasmosis (often used off-label or in specific formulations). 

ADMINISTRATION

  • By hand: For cooperative animals, the bolus may be placed directly into the mouth by hand.
  • By balling gun: A balling gun is a common veterinary instrument used to safely and effectively administer boluses to large animals, such as cattle, goats, and horses, by placing the medication at the back of the throat.
  • Dispersed in water: The bolus can be crushed and dispersed in water using a dosing bottle or drench for oral administration, particularly for smaller animals like chickens or where an animal refuses the solid form. 

DOSAGE

  • Cattle: 2 to 3 bolus per day for 3 to 5 days
  • Sheep, goat & pig: 1/2 to 1 bolus per day for 3 to 5 days
  • Intrauterine use: 1/2 to 1 bolus deep into the uterus for 3 to 5 days

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