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Marek’s Disease Virus Vaccine

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Marek’s Disease Virus Vaccine

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Innovax-ILT-IBD Vaccine

MSD's Innovax-ILT-IBD is a single-dose vaccine for poultry that provides long-term protection against three major diseases: Infectious Laryngotracheitis (ILT), Infectious Bursal Disease (IBD), and Marek's disease (MD).

Marek’s Disease Virus (MDV) vaccine is indicated for active immunization of healthy chickens (day-old chicks) to prevent mortality, reduce clinical signs (paralysis, tumors), and lessen lesions caused by virulent MDV strains

INDICATIONS

  • Target Species: Chickens
  • Protect against Mortality: Prevents widespread death in poultry flocks.
  • Reduce Clinical Signs: Lessens paralysis (leg/wing droop), vision problems (gray eyes), and behavioral changes.
  • Prevent Lesions: Minimizes tumors in organs (liver, spleen, heart, etc.) and enlarged peripheral nerves.
  • Early Protection: Provides immunity starting from a few days old, covering the highest risk period. 
  • Timing: In ovo (18-19 day embryos) or 1-day-old chicks (day-old).

ADMINISTRATION

For Day-Old Chicks (Subcutaneous Injection)

  • Timing: Day of hatch.
  • Site: Back of the neck, pinching the loose skin to create a pocket.
  • Method: Inject 0.2 mL under the skin, away from the head, using a 1 mL syringe and a 20-22 gauge, 3/8-1/2 inch needle.
  • Key Steps: Clean the injection site with alcohol, use sterile equipment, and place vaccinated chicks in a separate area to avoid unvaccinated birds. 
For Embryos (In Ovo)
  • Timing: Around day 18 of incubation.
  • Method: Automated injection systems deliver 0.05 mL or 0.10 mL directly into the egg.
  • Benefits: Widely used in commercial settings due to lower labor costs and precision. 
Preparation
  • Refrigeration: Keep vaccine refrigerated until use (often frozen in liquid nitrogen for some types).
  • Mixing: Thaw frozen vaccines quickly (around 90 seconds) and mix with sterile diluent.
  • Time Sensitive: Use the mixed vaccine within 1-2 hours
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