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Melengestrol acetate

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Melengestrol acetate

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CycleGuard 500 Liquid Feed Mix

Huvepharma’s CycleGuard 500 is a liquid feed additive containing melengestrol acetate designed to suppress estrus in heifers. Improves weight gain and feed efficiency. A CODEX Veterinary Medicine.

Huvepharma’s CycleGuard 500 Melengestrol acetate liquid feed mix (MGA) is a synthetic progestin, indicated for use in heifers.

INDICATIONS

  • For Heifers in Confinement:
    • Increased rate of weight gain (faster growth).
    • Improved feed efficiency (getting more weight gain per unit of feed).
    • Suppression of estrus (heat), which minimizes restlessness and feed wastage from cycling.
  • For Heifers Intended for Breeding (Replacement Heifers):
    • Suppression of estrus (heat) to manage reproductive cycles and synchronize breeding.
  • In Combination Feeds (with other drugs):
    • Can be combined with tylosin for liver abscess control.
    • Can be combined with monensin for prevention and control of coccidiosis

ADMINISTRATION

  • Feed Premix: MGA is a Type A medicated feed premix.
  • Batch Mixing: The premix is thoroughly blended into larger quantities of complete feed or protein/grain supplements.
  • Top-Dressing: It can also be top-dressed onto other feedstuffs for daily consumption.
  • Dosage: Usually 0.25 to 0.5 mg per head per day, depending on the goal (growth vs. estrus suppression). 
for Estrus Synchronization (Heifers):
  • MGA-Only: Feed for 14-18 days to suppress heat.
  • MGA-PGF2α Protocol: Feed MGA for 14 days, then withdraw; administer Prostaglandin F2α (PGF2α) 17-19 days after MGA withdrawal to induce synchronized estrus.
  • MGA-Select (MGA-GnRH-PGF2α): Feed MGA for 14 days, followed by GnRH 10-12 days after withdrawal, then PGF2α 7 days after GnRH for precise AI timing. 
  • Target Animals: Only effective in intact heifers; not for steers or spayed heifers.
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