Buserelin acetate is a gonadotropin-releasing factor agonist used to control reproduction in cattle, horses, and small pets.
INDICATIONS
CATTLE (Cows and Heifers)
- Ovarian Cysts: Treatment of follicular cysts, with or without symptoms of nymphomania (frequent or constant heat).
- Ovulation Induction: To induce ovulation or treat delayed ovulation.
- Estrus Synchronization: Used in conjunction with other hormones (like PGF2α) to synchronize estrous cycles for fixed-time artificial insemination (AI).
- Conception Rates: Improvement of pregnancy rates when administered at the time of insemination or during the early luteal phase (days 11–12 post-AI).
- Post-Partum Recovery: Early induction of the estrous cycle after calving to reduce the interval between calving and conception.
HORSES (Mares)
- Ovulation Timing: Induction of ovulation to synchronize it more closely with mating or artificial insemination.
- Follicular Cysts: Management of cystic ovarian disorders.
- Fertility Improvement: To enhance conception rates.
PIGS (Sows and Gilts)
- Fixed-Time AI: Induction of ovulation following estrus synchronization to facilitate a single, fixed-time artificial insemination program.
- Centralizing Ovulation: Shortening the interval from estrus to ovulation for better breeding outcomes.
RABBITS
- Conception & Ovulation: Induction of ovulation and improvement of conception rates in commercial does.
- Post-Partum Insemination: Induction of ovulation during insemination performed shortly after giving birth.
FISH (Rainbow Trout)
- Egg Binding: To facilitate “stripping” (the manual removal of eggs) and reduce mortality associated with egg binding.
ADMINISTRATION
- Preferred Route: For cattle, horses, pigs, and rabbits, the intramuscular route is generally preferred.
- Aseptic Precautions: Aseptic procedures must always be used during injection to prevent infection.
- Dosage: Varies by species and indication.
- Timing: Injection in relation to insemination or mating is crucial for efficacy.
