Lawsonia Intracellularis Vaccine
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Lawsonia intracellularis vaccine is indicated for healthy pigs and sometimes foals for the prevention or control Porcine Proliferative Enteropathy (PPE).
INDICATIONS
For Pigs
- Purpose: Active immunization against Lawsonia intracellularis (Ileitis/PPE).
- Reduces: Diarrhea, decreased weight gain, intestinal lesions, bacterial shedding, and mortality.
- Timing: Administer at least 3-4 weeks before expected infection; best results around 8 weeks prior to expected seroconversion.
- Usage: Can often be mixed with PCV2 and M. hyopneumoniae vaccines for multi-disease protection.
For Horses
- Purpose: Used off-label (intrarectally) to prevent Equine Proliferative Enteropathy (EPE) in foals.
- Benefits: Vaccinated foals show reduced clinical signs (like thickened intestines), less severe disease, and lower shedding compared to unvaccinated foals.
- Important Note: This is an off-label use; veterinarians must check state regulations.
Key Considerations
- Medication-Free Period: Must avoid antibiotics and disinfectants for at least 7 days around vaccination (3 days before/after) to prevent inactivation.
- Type of Vaccine: Live vaccines typically use oral routes, while inactivated vaccines often use IM injection.
- Target Species: Mostly pigs, but research also explores equine use.
- Timing: Vaccinate pigs from around 3 weeks of age.
ADMINISTRATION
- Drinking Water (Live Vaccines):
- Prepare by flushing water lines and ensuring no antimicrobials (e.g., for 3 days before/after).
- Add thawed/rehydrated vaccine to clean, untreated water.
- Pigs consume the water within 6 hours.
- Oral Drench/Gel (Live Vaccines):
- Administered directly into the mouth via syringe (drench) or special gel applicators.
- This method is faster and efficient for large groups, even before weaning.
- Intramuscular (IM) Injection (Inactivated Vaccines):
- A 2 mL dose injected into the neck muscle.
- Reconstituted with a special solvent or mixed with other vaccines.
Key Considerations
- Target Species: Mostly pigs, but research also explores equine use.
- Type of Vaccine: Live vaccines typically use oral routes, while inactivated vaccines often use IM injection.
- Timing: Vaccinate pigs from around 3 weeks of age.
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