INDICATIONS

• Induction of Ovulation: It is commonly used to induce ovulation (release of eggs from the ovary) in mares and rabbits, allowing for more accurate timing of mating or artificial insemination (AI).
• Ovarian Disorders: It is indicated for the treatment of ovarian disorders, specifically follicular cysts, which can cause irregular estrus cycles or nymphomania in cattle.
• Improved Conception/Pregnancy Rates: Administration at the time of AI, or several days afterward during the luteal phase, can improve overall conception and pregnancy rates in cows and mares.
• Estrus Synchronization: In conjunction with other hormones like prostaglandin F2α (PGF2α) analogues, it is used to synchronize the estrus (heat) cycles of groups of livestock, facilitating fixed-time artificial insemination (FTAI) programs and scheduled breeding.
• Postpartum Fertility: It can be used to induce an early postpartum estrus cycle and improve fertility in the period after calving.
• Increased Litter Size: In gilts (young female pigs), its use has been shown to improve farrowing outcomes, specifically leading to a potential increase in the number of total piglets born. 

ADMINISTRATION

• Cattle, Horses, and Rabbits: The intramuscular route is generally preferred, but it can also be administered subcutaneously or intravenously.
• Pigs: The intramuscular route is the preferred method.
• Fish (Trout): A single dose is administered per kg bodyweight to facilitate spawning.
• Aseptic Technique: Aseptic precautions must be observed during administration to prevent infection.
• Dosage: The dosage and timing are dependent on the species and the specific condition being treated (e.g., ovarian cysts, induction of ovulation, improvement of conception rate). A veterinarian determines the appropriate dose and schedule.